As the interest in non-surgical cosmetic procedures continues to grow year after year, so does the availability and variety of treatments. “Wrinkle Relaxers” was created to educate the consumer on 3 primary injectable Botulinum Toxin solutions available in the United States for the improvement of facial wrinkles and other indications. It is important to note that only BOTOX and DYSPORT have indications for cosmetic purposes to date. You will notice that the FDA approved indications are limited compared to the actual utilization of these products. (Since 1997, there has been over 155% increase in the total number of cosmetic procedures. Surgical procedures increased by more than 71%, and nonsurgical procedures increased by 228%. The top five nonsurgical cosmetic procedures in 2010 were: Botulinum Toxin Type A (2,437,165 procedures); hyaluronic acid (1,315,121 procedures); laser hair removal (936,270 procedures); laser skin resurfacing (562,706 procedures); chemical peel (493,896 procedures) ASAPS 2010 Statistics.)